Graduate Courses » 90625
90625 - Molecular Biophysics
Semester: Spring
An investigation of the forces that drive intra- and inter-molecular recognition, including hydrophobicity, electrostatics, and configurational entropy. Topics include the thermodynamics of protein folding and ligand binding and their relationships to chemical properties and three-dimensional structure; mathematical treatment of folding, binding, and linkage via partition functions; and the determinants of ligand binding specificity and kinetics. Advanced theory supplemented with primary literature.
