Patricia L. Clark » Image Gallery

The pertactin parallel β-helix topology provides an excellent model system to ask detailed questions about parallel β-sheet formation. We are also investigating the outer membrane secretion mechanism of this and related virulence factors from pathogenic gram-negative bacteria. Red stick figures highlight the locations of seven Trp residues, used for fluorescence kinetic measurements.

Contact Information

• Associate Professor
  Graduate Studies Representative - Biochemistry
• Office: 445 SHCB
• Phone: 574.631.8353
• Contact by Email
• Group Website

Primary Research Areas

• Biochemistry

Research Specialties

• Drug Design & Discovery
• Molecular and Cell Biology
• Nanotechnology
• Structural Biology
• Biophysics
• Molecular Medicine

Lab Personnel

• Richard N. Besingi
• Thomas F. Clarke
• Mary Finn
• Jonathan P. Renn
• Jenna L. Rose
• Ian Sander
• Krastyu Ugrinov
• Esther Braselmann
  Visiting Researcher
• Kathleen Gonderman
  Undergraduate Researcher
• Benjamin Hechler
  Undergraduate Researcher

Courses

• Molecular Biophysics
• Fundamentals of Biochemistry
• Principles of Biochemistry
• Special Topics in Biochemistry - The Life Cycle of Proteins